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Investigating the influence of environmental factors on the incidence of renal disease with compositional data analysis using balances

This research uses an urban soil geochemistry database of elemental concentration to examine the potential relationship between Standardised Incidence Rates (SIRs) of Chronic Kidney Disease (CKD) of uncertain aetiology (CKDu), and cumulative low level geogenic and diffuse anthropogenic contamination of soils with PTEs. A compositional data analysis approach was applied to determine the elemental balance(s) of the geochemical data showing the greatest association with CKDu. The research concludes that both anthropogenic and geogenic factors may be contributing influences to explain high incidences of CKDu, up to 12 times greater in some Super Output Areas (SOAs) than would be expected for the average population. The role of As, Cr, Cu, Pb, Sb and Mo was highlighted, which may be linked to anthropogenic sources such as historical industrial sources, atmospheric pollution deposition and brake emissions. Geogenic factors were shown to be important in areas with elevated relative concentrations of naturally occurring potentially toxic elements (PTEs).

Ketersediaan
91551.136Perpustakaan BIG (Eksternal Harddisk)Tersedia
Informasi Detail
Judul Seri
Applied Computing and Geoscience - Open Access
No. Panggil
551.136
Penerbit
Amsterdam : Elsevier.,
Deskripsi Fisik
7 hlm PDF, 1.529 KB
Bahasa
Inggris
ISBN/ISSN
2590-1974
Klasifikasi
551.136
Tipe Isi
text
Tipe Media
-
Tipe Pembawa
-
Edisi
Vol.6, June 2020
Subjek
Geochemistry
Chronic kidney disease
Uncertain aetiology
Info Detail Spesifik
-
Pernyataan Tanggungjawab
Versi lain/terkait

Tidak tersedia versi lain

Lampiran Berkas
  • Investigating the influence of environmental factors on the incidence of renal disease with compositional data analysis using balances
    This research uses an urban soil geochemistry database of elemental concentration to examine the potential relationship between Standardised Incidence Rates (SIRs) of Chronic Kidney Disease (CKD) of uncertain aetiology (CKDu), and cumulative low level geogenic and diffuse anthropogenic contamination of soils with PTEs. A compositional data analysis approach was applied to determine the elemental balance(s) of the geochemical data showing the greatest association with CKDu. The research concludes that both anthropogenic and geogenic factors may be contributing influences to explain high incidences of CKDu, up to 12 times greater in some Super Output Areas (SOAs) than would be expected for the average population. The role of As, Cr, Cu, Pb, Sb and Mo was highlighted, which may be linked to anthropogenic sources such as historical industrial sources, atmospheric pollution deposition and brake emissions. Geogenic factors were shown to be important in areas with elevated relative concentrations of naturally occurring potentially toxic elements (PTEs).
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